@phdthesis{Terholsen2023,
  author    = {Henrik Terholsen},
  title     = {Enzymatic valorization of sustainable carbon sources},
  journal    = {Enzymatische Verwertung von nachhaltigen Kohlenstoffquellen},
  url       = {https://nbn-resolving.org/urn:nbn:de:gbv:9-opus-85342},
  pages     = {198},
  year      = {2023},
  abstract  = {In this thesis, new catalysts as well as unprecedented approaches for the valorization of sustainable carbon sources were investigated. The first part deals with the design of catalysts for photocatalytic CO2 reduction (Articles I\&II). The promiscuous activity of phenolic acid decarboxylase from Bacillus subtilis (BsPAD) was found to catalyze CO2 reduction (Article I). This cofactor-free enzyme could facilitate the replacement of (noble) metal catalysts regularly employed in CO2 reduction. Based on these findings, additional enzyme catalysts were identified for photocatalytic CO2 reduction. The second part (Articles III-VII) focuses on the valorization of resources obtained from biomass, such as olive mill waste water or lignin, by the promising acyltransferases/hydrolase PestE from Pyrobaculum calidifontis VA1 (Articles IV-VII). The potential of PestE for the valorization of sustainable sources has been demonstrated by enzyme engineering and use in (chemo)enzymatic cascade reactions leading to value-added products.},
  language  = {en}
}