@phdthesis{Beier2017,
  author    = {Andy Beier},
  title     = {Discovery and Protein Engineering of Baeyer-Villiger monooxygenases},
  journal    = {Entdeckung und Protein Engineering von Baeyer-Villiger Monooxygenasen},
  url       = {https://nbn-resolving.org/urn:nbn:de:gbv:9-002918-2},
  year      = {2017},
  abstract  = {In this work, the discovery, expression and characterization of new eukaryotic Baeyer-Villiger monooxygenases (BVMOs) from yeasts has been shown. A rational design of one of these enzymes led to the identification of key residues to alter the sulfoxidation activity of this group of enzymes. Additionally, in another rational design approach, the cofactor specificity of the BVMO cyclohexanone monooxygenase from Acinetobacter calcoaceticus could be substantially altered to accept the much cheaper and therefore industrially more relevant cofactor NADH.},
  language  = {en}
}