@phdthesis{Eichele2010,
  author    = {Heike Eichele},
  title     = {Go/NoGo Performance in Boys with Tourette Syndrome},
  journal    = {Go/NoGo Leistung bei Jungs mit Tourette Syndrom},
  url       = {https://nbn-resolving.org/urn:nbn:de:gbv:9-000846-2},
  year      = {2010},
  abstract  = {Tourette syndrome has been associated with impairments of performance monitoring and alterations of attentional and executive functions. This impairment has been linked to fronto-striatal dysfunctions, which comprise the same braincircuits that are actively engaged in the suppression of tics. We compared behavioral performance and performance monitoring in nineteen boys with Tourette syndrome (TS) (mean age 12.64 years, ± 2.05) and nineteen age-matched controls (mean age 13.16 years, ± 2.29) in a Go/NoGo paradigm. This paradigm was designed to test for problems with inhibition and attention when withholding the response to NoGo targets following repetitive Go targets. The results indicated similar performance accuracy in the TS group and the control group. TS participants showed the expected pattern of Post-Error Slowing, but responded significantly also slower to correct Go trials than the controls. The reaction times (RT) to NoGo targets in commission errors, however, did not differ between the groups. The results suggest that boys with TS develop inhibitory adaptive strategies (overall slower reaction times) to maintain high performance accuracy. These effects may be suspended prior to and during NoGo commission errors.},
  language  = {en}
}