@phdthesis{Xu2012,
  author    = {Jiacui Xu},
  title     = {Ribozymes for Aminoacylation},
  journal    = {Ribozyme f{\"u}r die Aminoacylierung},
  url       = {https://nbn-resolving.org/urn:nbn:de:gbv:9-001267-4},
  year      = {2012},
  abstract  = {Aminoacyl-tRNA synthetases (aaRS) are at the heart of modern translation, catalyzing the accurate biosynthesis of aminoacyl-tRNAs. According to the RNA world hypothesis, the early translation system should have aminoacylation ribozymes for RNA aminoacylation. For this, an aaRS ribozyme system, consisting of the KK13 ribozyme and the C3a ribozyme was successfully designed, which can perform both amino acid activation and aminoacyl transfer reaction. Generation of such aminoacylation ribozyme system would fill up the gap between the RNA world and the modern biological world. In addition, two types of diversified aminoacylation ribozymes, symmetrical ribozymes and self-assembling ribozymes were successfully developed, which may have great meaning in the origin of life.},
  language  = {en}
}