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Air Ambulance: Antimicrobial Power of Bacterial Volatiles

  • We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be bacterial volatiles. Volatiles are ubiquitous produced, chemically divers and playing essential roles in intra- and interspecies interactions like communication and antimicrobial defense. In the last years, an increasing number of studies showed bioactivities of bacterial volatiles, including antibacterial, antifungal and anti-oomycete activities, indicating bacterial volatiles as an exciting source for novel antimicrobial compounds. In this review we introduce the chemical diversity of bacterial volatiles, their antimicrobial activities and methods for testing this activity. Concluding, we discuss the possibility of using antimicrobial volatiles to antagonize the antimicrobial resistance crisis.

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Author: Alexander Lammers, Michael Lalk, Paolina Garbeva
Parent Title (English):Antibiotics
Place of publication:Basel
Editor: Laura Cendron
Document Type:Article
Date of first Publication:2022/01/14
Release Date:2022/07/05
Tag:antibacterial; antibiotics; antifungal; antimicrobial resistance crisis; chemical ecology; metabolomics; volatile organic compounds; volatiles
GND Keyword:-
Article Number:109
Page Number:15
Faculties:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie und Biochemie
Licence (German):License LogoCreative Commons - Namensnennung