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Bitte verwenden Sie diesen Link, wenn Sie dieses Dokument zitieren oder verlinken wollen: https://nbn-resolving.org/urn:nbn:de:gbv:9-opus-30773

Antibacterial Activity of Cold Atmospheric Pressure Argon Plasma against 78 Genetically Different (mecA, luk-P, agr or Capsular Polysaccharide Type) Staphylococcus aureus Strains

  • Previous studies on the antimicrobial activity of cold atmospheric pressure argon plasma showed varying effects against mecA<sup>+</sup> or mecA<sup>-</sup>Staphylococcus aureus strains. This observation may have important clinical and epidemiological implications. Here, the antibacterial activity of argon plasma was investigated against 78 genetically different S. aureus strains, stratified by mecA, luk-P, agr1-4, or the cell wall capsule polysaccharide types 5 and 8. kINPen09® served as the plasma source for all experiments. On agar plates, mecA<sup>+</sup>luk-P<sup>-</sup>S. aureus strains showed a decreased susceptibility against plasma compared to other S. aureus strains. This study underlines the high complexity of microbial defence against antimicrobial treatment and confirms a previously reported strain-dependent susceptibility of S. aureus to plasma treatment.

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Metadaten
Author: Rutger Matthes, Anne Lührman, Silva Holtfreter, Julia Kolata, Dörte Radke, Nils-Olaf Hübner, Ojan Assadian, Axel Kramer
URN:urn:nbn:de:gbv:9-opus-30773
DOI:https://doi.org/10.1159/000443210
ISSN:1660-5527
ISSN:1660-5535
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/27035668
Parent Title (English):Skin Pharmacology and Physiology
Publisher:S. Karger AG
Place of publication:Basel, Switzerland
Document Type:Article
Language:English
Date of first Publication:2016/04/02
Release Date:2020/09/29
Tag:Antibacterial efficacy; Cold atmospheric pressure plasma; Methicillin-resistant; Tolerability; Virulence
GND Keyword:-
Volume:29
Issue:2
First Page:83
Last Page:91
Faculties:Universitätsmedizin / Institut für Community Medicine
Licence (German):License LogoUrheberrechtlich geschützt