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Generation of two isogenic iPSC lines from a healthy male donor of European ancestry
- We have created two isogenic iPSC lines from fibroblasts of a healthy male donor of European ancestry. The cell lines express common pluripotency markers, are free of chromosomal aberrations and are able to differentiate into cells of all three germ layers. These iPSC are now a resource for genome editing with the aim of creating models of genetic disorders without having to depend on patient cells.
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| Author: | Stephanie Edwards, Lisa HagenauORCiD, Björn Nowack, Johannes Rhode, Mohammed F. HossainORCiD, Ana Tzvetkova, Lars R. JensenORCiD, Andreas W. KussORCiD |
|---|---|
| URN: | urn:nbn:de:gbv:9-opus-116940 |
| DOI: | https://doi.org/10.1016/j.scr.2024.103403 |
| ISSN: | 1873-5061 |
| Parent Title (English): | Stem Cell Research |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Date of Publication (online): | 2024/03/24 |
| Date of first Publication: | 2024/06/01 |
| Release Date: | 2024/10/16 |
| Volume: | 77 |
| Article Number: | 103403 |
| Page Number: | 4 |
| Faculties: | Universitätsmedizin / Interfakultäres Institut für Genetik und Funktionelle Genomforschung (UMG) |
| Collections: | Artikel aus DFG-gefördertem Publikationsfonds |
| Licence (German): |  Creative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung 4.0 International |