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Rare clival localization of an eosinophilic granuloma: illustrative case
- BACKGROUND Eosinophilic granuloma (EG) belongs to the family of Langerhans cell histiocytosis (LCH) and is considered to be a benign disease typically found in children younger than 15 years of age. Here, the authors describe an EG of unusual localization and clinical presentation. OBSERVATIONS The authors report a 9-year-old girl with an EG presenting as an osteolytic lesion of the clivus. After transsphenoidal resection and histological confirmation, adjuvant chemotherapy was initiated. Presenting signs and symptoms were weight loss, episodic grimacing, and moderate ballism-like movements. After a follow-up-period of 32 months, the patient presented with a total resolution of initial symptoms and no further tumor growth. LESSONS Although these lesions are rare, one should consider EG as a differential diagnosis when confronted with osteolytic lesions of the clivus.
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| Author: | Martin E. Weidemeier, Steffen Fleck, Werner Hosemann, Silke Vogelgesang, Karoline Ehlert, Holger N. LodeORCiD, Henry W. S. Schroeder |
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| URN: | urn:nbn:de:gbv:9-opus-105661 |
| DOI: | https://doi.org/10.3171/CASE22490 |
| ISSN: | 2694-1902 |
| Parent Title (English): | Journal of Neurosurgery (JNS): Case lessons |
| Publisher: | American Association of Neurological Surgeons (AANS) |
| Place of publication: | Rolling Meadows, IL |
| Document Type: | Article |
| Language: | English |
| Date of first Publication: | 2023/06/19 |
| Release Date: | 2024/01/29 |
| Tag: | cranial; eosinophilic granuloma; neurosurgical treatment; oncology; pediatric; radiotherapy |
| Volume: | 5 |
| Issue: | 25 |
| Article Number: | CASE22490 |
| Page Number: | 4 |
| Faculties: | Universitätsmedizin / Klinik und Poliklinik für Neurochirurgie |
| Collections: | Artikel aus DFG-gefördertem Publikationsfonds |
| Licence (German): |  Creative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung |