Open Access

Armin Jentsch, Frances Hoferichter, Diana Raufelder, Geja Hageman, Lou Maas

• Abstract Background In the present study, we investigated the association between sensory processing sensitivity (SPS) and telomere length (TL), which is considered a biomarker of cellular aging. SPS is an individual characteristic describing increased perception and procession of inner or outer stimuli, and is positively related to self‐perceived stress. Methods We recruited 82 healthy adolescents aged 13–16 from secondary schools in Germany. SPS was measured with the Highly Sensitive Person Scale, and TL was determined by a multiplex quantitative PCR method. Results Our results show that students with higher values of SPS are likely to have shorter telomeres (β = 0.337, p = .001), when adjusting for sex, socioeconomic status, age, and body mass index. These findings are also independent of the negative impact of stress students might have perceived shortly before data collection. Conclusions Our analysis suggests that students who struggle with low sensory threshold are likely to have shorter telomeres.