Refine
Document Type
- Article (7)
Language
- English (7)
Has Fulltext
- yes (7)
Is part of the Bibliography
- no (7)
Keywords
- - (4)
- proteomics (4)
- castration-resistant prostate cancer (2)
- prostate cancer (2)
- 1,4-naphthoquinones (1)
- CNS (1)
- FTSJ1 (1)
- M1 macrophage (1)
- M2 macrophage (1)
- NF-κB signal transduction pathway (1)
- Oxidative burst (1)
- Phagocytosis (1)
- Reactive oxygen species (1)
- SDS-SP3 protocol (1)
- TLR4 signaling (1)
- UPS (1)
- Warburg effect (1)
- cellular regulation (1)
- formalin fixed and embedded brain sample (1)
- glucose uptake (1)
- immunoproteasome (1)
- long-term potentiation (1)
- mass spectrometry (1)
- microRNA (1)
- microglia (1)
- mitochondria (1)
- natural products (1)
- neuroinflammation (1)
- neuronal plasticity (1)
- protein preparation (1)
- proteostasis (1)
- sea urchins (1)
- tRNA methyl transferase (1)
- thioglucoside conjugates (1)
Institute
- Abteilung für Mikrobiologie und Molekularbiologie (2)
- Institut für Med. Biochemie u. Molekularbiologie (2)
- Institut für Anatomie und Zellbiologie (1)
- Institut für Biochemie (1)
- Institut für Mikrobiologie - Abteilung für Genetik & Biochemie (1)
- Interfakultäres Institut für Genetik und Funktionelle Genomforschung (MNF) (1)
- Interfakultäres Institut für Genetik und Funktionelle Genomforschung (UMG) (1)
Publisher
- MDPI (5)
- Frontiers Media S.A. (1)
- Springer Nature (1)
Macrophages are cells of the innate immune system and represent an important component of the first-line defense against pathogens and tumor cells. Here, their diverse functions in inflammation and tumor defense are described, and the mechanisms, tools, and activation pathways and states applied are presented. The main focus is on the role and origin of reactive oxygen species (ROS), the important signal pathways TLR/NF-κB, and the M1/M2 polarization of macrophages.