Article
Refine
Year of publication
Document Type
- Article (99) (remove)
Language
- English (95)
- German (3)
- Multiple languages (1)
Has Fulltext
- yes (99)
Is part of the Bibliography
- no (99)
Keywords
- - (44)
- dementia (7)
- GWAS (3)
- epidemiology (3)
- pandemic (3)
- physical activity (3)
- COVID-19 (2)
- Chronic kidney disease (2)
- Dementia (2)
- Developmental screening (2)
- Germany (2)
- Iodine (2)
- Primary care (2)
- Telemedicine (2)
- association study (2)
- bias (2)
- causal inference (2)
- cognitive function (2)
- deployment (2)
- depression (2)
- guidelines (2)
- health information exchange (2)
- inactive nurses (2)
- machine learning (2)
- mendelian randomization (2)
- metabolic syndrome (2)
- mortality (2)
- nursing shortage (2)
- obesity (2)
- participatory research (2)
- patient preferences (2)
- patient-centered care (2)
- prevention (2)
- primary care (2)
- quality of life (2)
- record linkage (2)
- return (2)
- statistical methods (2)
- symptoms (2)
- 3,5-Diiodothyronine (1)
- ACE inhibitors (1)
- ADHD (1)
- ADL (1)
- ARB (1)
- AUDIT‐C (1)
- Ability to work (1)
- Acceptance (1)
- Advanced nursing practice (1)
- Advanced nursing roles (1)
- AgeWell.de (1)
- Agreement (1)
- Allogeneic blood (1)
- Allogeneic transfusion (1)
- Alzheimer's disease (1)
- Alzheimer’s disease (1)
- Ambulante Versorgung (1)
- Ambulatory care (1)
- Ambulatory geriatric rehabilitation (1)
- Antibacterial efficacy (1)
- At-risk drinking (1)
- Attention (1)
- At‐risk Drinking (1)
- Aufgabenneuverteilung (1)
- BA.2 (1)
- BA.5 (1)
- Bland-Altman Plots (1)
- Blood donation (1)
- Blood safety (1)
- Blood supply (1)
- Blood transfusion (1)
- Breast cancer (1)
- Brief intervention (1)
- Broad consent (1)
- COPD (1)
- COVID-19 pandemic (1)
- COVID-19-related future anxiety (1)
- Cardiovascular risk factors (1)
- Care and case management (1)
- Children (1)
- Chronic renal failure (1)
- Chronische Niereninsuffizienz (1)
- Claims data (1)
- Cold atmospheric pressure plasma (1)
- Collaborative care (1)
- Compositional data analysis (1)
- Concentration (1)
- Consent implementation (1)
- Consent management (1)
- Consent process (1)
- Curriculum (1)
- Dark Future Scale for children (1)
- Dear Doctor letter (1)
- Delegation (1)
- Demenz (1)
- Democratic Republic of the Congo (DRC) (1)
- Demographic change (1)
- Developmental risks (1)
- Disability (1)
- Donor research (1)
- Donors (1)
- Drinking Patterns (1)
- Dropout (1)
- Early prevention (1)
- Eingeschränkte Nierenfunktion (1)
- Elderly (1)
- Elective surgery (1)
- Endoscopic breast ductoscopy (1)
- Epidemiology (1)
- Equity (1)
- ExWAS (1)
- Expert consensus (1)
- Expertenkonsens (1)
- FAIR data principles (1)
- FHIR (1)
- Facharztausbildung (1)
- Feedback (1)
- Financial risk protection (1)
- Functional health (1)
- Gene expression (1)
- General outpatient palliative care (GOPC) (1)
- General practitioner (1)
- Geriatric multimorbidity (1)
- Geriatrics (1)
- Growth curve model (1)
- Guideline recommendations (1)
- Health care costs (1)
- Health claims data (1)
- Health economic research (1)
- Health insurance (1)
- Health outcomes (1)
- Health service research (1)
- Health-related quality of life (HRQoL) (1)
- IADL (1)
- Impaired renal function (1)
- Incapacity to work (1)
- Informed Consent (1)
- Inhaltsanalyse (1)
- Intracellular localization (1)
- Intraductal lesion (1)
- Iodine status (1)
- KIDSCREEN-10 (1)
- Legal requirements (1)
- Lockdown (1)
- Longitudinal (1)
- MAR (1)
- MNAR (1)
- MRI (1)
- Management (1)
- Matched cohortstudy (1)
- Measurement (1)
- Measurement error (1)
- Medical data management (1)
- Mental health (1)
- Mental health problems (1)
- Mental problems (1)
- Mental strain (1)
- Mental stress (1)
- Methicillin-resistant (1)
- Method-comparison studies (1)
- Multiple sclerosis (1)
- Multivariate analysis (1)
- NAFLD (1)
- NMR spectroscopy (1)
- Nephrology (1)
- Nephrology referral (1)
- Nipple discharge (1)
- Non-small cell lung cancer (1)
- Nursing (1)
- Observational study (1)
- Older adults (1)
- Omicron (1)
- Out-of-pocket (1)
- Outcomes research (1)
- Outpatient care (1)
- Ovarian cancer (1)
- PAI-1 RNA-binding protein 1 (1)
- PRISMA (1)
- Palliative care (1)
- Parkinson's disease (1)
- Participant attrition (1)
- Patient preferences (1)
- Patient rights (1)
- Patients (1)
- Pediatric inflammatory bowel disease (PIBD) (1)
- Personalized medicine (1)
- Physical health (1)
- Plasminogen activator inhibitor 1 (1)
- Policy (1)
- Postpartum period (1)
- Precision medicine program (1)
- Prediction (1)
- Preferred Reporting Items for Systematic Reviews and Meta-Analyse (1)
- Pregnancy (1)
- Pregnant women (1)
- Preschool (1)
- Preschools (1)
- Prevention (1)
- Prolonged sitting (1)
- Propensity score matching (1)
- Psychiatric outpatients (1)
- Psychiatry (1)
- Public Health (1)
- Public health (1)
- Quality assessment (1)
- Quality of life (1)
- Qualitätsüberprüfung (1)
- R project for statistical computing (1)
- RCT (1)
- Real-world data (1)
- Red blood cell concentrate (1)
- Referral (1)
- Registry (1)
- Reliability (1)
- Resilience (1)
- Rural (1)
- SARS-CoV-2 (1)
- SARS-CoV-2 infections (1)
- SNP-specific alpha-level (1)
- Satisfaction (1)
- Sedentary behaviour patterns (1)
- Sedentary breaks (1)
- Sedentary time (1)
- Self-rated health (1)
- Smoking cessation (1)
- Social inequalities (1)
- Social inequality (1)
- Social law (1)
- Social participation (1)
- Specialized outpatient palliative care (SOPC) (1)
- Study protocol (1)
- Substitution (1)
- Survival (1)
- TSH (1)
- Targeted therapies (1)
- Tasks (1)
- Telemedical treatment (1)
- Telepsychiatry (1)
- Thyroglobulin (1)
- Thyroid (1)
- Thyroid hormone (1)
- Thyroid imaging (1)
- Thyroid-stimulating hormone (1)
- Tolerability (1)
- Trajectories (1)
- Transfusion (1)
- Treatment guidelines (1)
- Trigonelline (1)
- Universal Health coverage (1)
- Urinary iodine excretion (1)
- Urine metabolome (1)
- Validity (1)
- Varenicline (1)
- Variability (1)
- Virulence (1)
- Vorschriften (1)
- WHOQOL-BREF (1)
- WHOQOL-OLD (1)
- Whole blood (1)
- adolescence (1)
- adults (1)
- affective disorders (1)
- aged (1)
- alcohol (1)
- alcohol dependence severity (1)
- ambulante Versorgung (1)
- amiloride-sensitive sodium channel ENaC (1)
- analytic hierarchy process (1)
- anemia (1)
- anthropometry (1)
- area deprivation (1)
- artificial intelligence (1)
- attributes (1)
- barrier analysis (1)
- baseline imbalance (1)
- best subset selection (1)
- biomedical (1)
- bipolar disorder (1)
- blood count (1)
- body mass index (1)
- body weights and measures (1)
- brief intervention (1)
- calibration (1)
- cardiac failure (1)
- cardiometabolic diseases (1)
- cardiopulmonary disease (1)
- care (1)
- care management (1)
- case-control study (1)
- chronic (health) condition (1)
- chronic disease (1)
- claims data (1)
- clinical innovation (1)
- cluster (1)
- cluster-randomized controlled trial (1)
- cohorts (1)
- colocalization (1)
- community-based participatory research (1)
- comorbidity (1)
- conditional association analysis (1)
- consolidated framework for implementation research (1)
- content analysis (1)
- continuous outcome (1)
- control measures (1)
- cortisol (1)
- crisis (1)
- curriculum (1)
- cystic fibrosis (1)
- data quality (1)
- data quality monitoring (1)
- data reporting (1)
- data stewardship (1)
- dementia care (1)
- determinants (1)
- diabetes (1)
- diabetes mellitus (1)
- diagnostic techniques and procedures (1)
- diet (1)
- disaster nursing (1)
- disease recognition (1)
- distribution (1)
- dual RAS blockade (1)
- dyspnea (1)
- eHealth (1)
- education (1)
- electronic health records (1)
- enable-cluster (1)
- estimated glomerular filtration rate (eGFR) (1)
- exploratory data analysis (1)
- expression quantitative trait loci (eQTL) (1)
- fT3 (1)
- fT4 (1)
- fatigue (1)
- findable, accessible, interoperable, and reusable data principles (1)
- former nurses (1)
- general population (1)
- general population sample (1)
- general practitioner (1)
- genome-wide association studies (GWAS) (1)
- geriatrics (1)
- glucose homeostasis (1)
- glucose metabolism (1)
- health information network (1)
- health research (1)
- health services research (1)
- health-related quality of life (HRQL) (1)
- healthcare (1)
- healthcare utilization (1)
- hearing impairment (1)
- hepatic steatosis (1)
- hospitalization (1)
- implementation (1)
- implementation research (1)
- imputation (1)
- incidence (1)
- income (1)
- individual participant data (1)
- individualised intervention (1)
- individualized feedback (1)
- information retrieval (1)
- initial data analysis (1)
- insurance claims (1)
- interprofessional health care (1)
- interprofessionelle Zusammenarbeit (1)
- intervention (1)
- lack of concentration (1)
- lack of energy (1)
- latent class (1)
- lifestyle (1)
- lipid profile (1)
- longitudinal cohort study (1)
- low back pain (1)
- macrovascular disease (1)
- magnetic resonance imaging (1)
- malnutrition (1)
- mediation (1)
- medicine (1)
- mental health (1)
- mental illness (1)
- metabolic phenotypes (1)
- metabolome (1)
- metabolomics (1)
- metabotypes (1)
- methodology (1)
- mild cognitive impairment (1)
- modifier gene (1)
- moving study (1)
- multi-criteria decision analysis (1)
- multimorbidity (1)
- multivariate regression analysis (1)
- neurocognitive disorders (1)
- non-randomized studies (1)
- nursing (1)
- nursing home (1)
- nursing workforce (1)
- oral contraceptives (1)
- oral nutritional supplement (1)
- outpatient care (1)
- palliative care (1)
- patient participation (1)
- patient-reported outcome (1)
- perceived stress scale PSS-10 (1)
- person-centered care (1)
- personal data (1)
- pharmacoepidemiology (1)
- phenotyping (1)
- population-based imaging (1)
- population-based studies (1)
- postacute care (1)
- postgraduate medical education (1)
- postgraduate medical training (1)
- postgraduierte medizinische Ausbildung (1)
- prediabetes (1)
- prevalence (1)
- proactive coping: turnover (1)
- public health (1)
- qualitative analysis (1)
- qualitative research (1)
- questionnaire development (1)
- radiomics (1)
- regional differences (1)
- register (1)
- regulations (1)
- reserve (1)
- residency (1)
- routine surveillance data (1)
- rural (1)
- school children (1)
- school principals (1)
- schools and pre-schools (1)
- scoping review (1)
- sensory impairments (1)
- shared decision making (1)
- signal transduction (1)
- social isolation (1)
- social networking (1)
- social participation (1)
- spatial accessibility (1)
- specialty training (1)
- spleen volume (1)
- standard (1)
- study protocol (1)
- survey (1)
- task shifting (1)
- teachers (1)
- technical acceptance (1)
- telemedicine (1)
- texture-modified diet (1)
- thyroid (1)
- trace amine-associated receptor 1 (1)
- trajectory (1)
- transition (1)
- translational research (1)
- trial (1)
- usability (1)
- variants (1)
- vision loss (1)
- weight regulation (1)
- whole-body magnetic resonance imaging (1)
- whole-exome sequencing (1)
- ‘Medical Informatics Initiative’ (1)
Institute
- Institut für Community Medicine (99) (remove)
Publisher
- MDPI (21)
- BioMed Central (BMC) (19)
- Frontiers Media S.A. (14)
- S. Karger AG (12)
- Wiley (7)
- Public Library of Science (PLoS) (6)
- Nature Publishing Group (4)
- BMJ Publishing Group (3)
- JMIR Publications (3)
- Springer Nature (2)
Effectiveness of Varenicline as an Aid to Smoking Cessation in Primary Care: An Observational Study
(2012)
Aims: Although varenicline is commonly prescribed in primary care, information on smoking-related comorbidities and the effectiveness of varenicline in this context in Germany is scarce. This study assessed the efficacy and safety of varenicline in a large sample of patients seeking smoking cessation treatment through their general practitioners. The frequency of comorbidities was also evaluated. Methods: This was a 12-week, prospective, observational, non-comparative phase IV trial conducted in Germany. Abstinence rates at week 12 were evaluated by verbal reporting using the nicotine use inventory. Results: Overall, 1,391 subjects were enrolled; 1,177 received study medication and were evaluated for effectiveness and safety. At the end of the study, 71.1% (95% confidence interval 68.5–73.7) of subjects were abstinent. There were a total of 205 all-causality adverse events; 2.2% were classified as serious or severe. There were no fatal adverse events. At inclusion, 66.7% of participants had at least 1 concurrent comorbidity, with chronic obstructive pulmonary disease (35.5%), hypertension (29.6%) and depression (10.4%) being the most commonly reported. Conclusion: These real-world data indicate that varenicline is an effective and well-tolerated smoking cessation treatment when used in the primary care setting including patients with smoking-related comorbidities.