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“Blood for Blood”? Personal Motives and Deterrents for Blood Donation in the German Population
(2021)
‘Chameleonic' Serological Findings Leading to Life-Threatening Hemolytic Transfusion Reactions
(2015)
Background: The phenomena of co-incidence of transfusion-induced allo- and autoantibodies, blockage and/or loss of red blood cell (RBC) antigens are conspicuous and may result in confusion and misdiagnosis. Case Report: A 67-year-old female was transferred to the intensive care unit due to hemolysis which developed 2 days following transfusion of three Rh(D)-negative RBC units in the presence of strongly reactive autoantibodies. Standard serological testing and genotyping were performed. Upon arrival, the patient was typed as Ccddee. Her hemolysis was decompensated, and an immediate blood transfusion was required. In addition, direct and indirect antiglobulin tests (DAT and IAT) as well as the eluate were strongly positive. Emergency transfusion of Rh(D)-negative RBCs resulted in increased hemolysis and renal failure. An exhaustive testing revealed anti-D, anti-c, CCddee phenotype and CCD.ee genotype. Three units of cryopreserved CCddee RBCs were transfused, and the patient's condition immediately improved. The discrepancy between Rh-D phenotyping and genotyping was likely caused by masking of the D-epitopes by the autoantibodies. In fact, further enquiry revealed that the patient had been phenotyped as Rh(D)-positive 6 months ago and had been transfused at that time following hip surgery. Conclusion: The phenomena of transfusion-induced autoantibodies, masked alloantibodies, antigen blockage and/or loss are rare but important features which should be considered in patients presenting with autoimmune hemolytic anemia and/or hemolytic transfusion reactions.
β-Phenylalanine Ester Synthesis from Stable β-Keto Ester Substrate Using Engineered ω-Transaminases
(2018)
Summary
The present article deals with Easy-to-read Russian. It focuses on the level of syntax which is mainly characterized by the avoidance of complex sentence structures. The necessity to write sentences that are as short and simple as possible is intuitively comprehensible, but often difficult to implement in practice since Easy-to-read texts also have to express causal, final or many other relations. Suggestions for avoiding complex syntactic structures in Russian are submitted and put up for discussion by consulting results and important proposals of studies about German “Leichte Sprache”. This includes both clause constructions and complex sentences with their individual subgroups as well as asyndetic compound sentences. On the whole, the study is intended to make a linguistically substantiated contribution to the development of Easy-to-read Russian, for which there are only initial approaches available today.
Zerstückte Laufbahn
(2016)
Karl Philipp Moritz’ Roman Anton Reiser (1785–1790) schildert die Laufbahn
seines Titelhelden.1 Trotz aller Bewegungsmetaphorik, die bereits in dessen Namen eingetragen ist, erscheint diese – der zeitgenössischen Semantik entsprechend2 – dabei zumindest nicht als rein linearer Prozess: Reisers Laufbahn ist
nämlich nicht nur durch progredierende, sondern auch durch zirkuläre, retardie
Zerstückte Laufbahn
(2016)