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Patient-reported & Health Economic Outcomes for Low-value Medications in Patients Living with Dementia
- Background This study aimed to analyze the impact of low-value medications (Lvm), that is, medications unlikely to benefit patients but to cause harm, on patient-centered outcomes over 24 months. Methods This analysis was based on longitudinal data of patients with dementia. The impact of Lvm on health-related quality of life (HRQoL), hospitalizations, and health care costs were assessed using multiple regression models. Results Over 24 months, Lvm was highly prevalent and significantly increased the risk of hospitalization, increased health care costs, and reduced patients' HRQoL. Conclusion More than every second patient received Lvm, negatively impacting patient-reported HRQoL, hospitalizations, and costs. Innovative approaches are needed to encourage prescribers to avoid and replace Lvm in dementia care.
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| Author: | Moritz Paul Platen |
|---|---|
| URN: | urn:nbn:de:gbv:9-opus-87069 |
| Title Additional (German): | Patientenbezogene und gesundheitsökonomische Outcomes von Low-value-Medications bei Menschen mit Demenz |
| Referee: | Prof. Dr. Steffen Fleßa, Prof. Dr. Wolfgang HoffmannORCiD |
| Advisor: | PD Dr. Bernhard Michalowsky |
| Document Type: | Doctoral Thesis |
| Language: | English |
| Year of Completion: | 2023 |
| Date of first Publication: | 2023/06/30 |
| Granting Institution: | Universität Greifswald, Rechts- und Staatswissenschaftliche Fakultät |
| Date of final exam: | 2023/06/22 |
| Release Date: | 2023/06/30 |
| Tag: | Low-value medication |
| GND Keyword: | Arzneiverordnung |
| Page Number: | 145 |
| Faculties: | Rechts- und Staatswissenschaftliche Fakultät / Wirtschaftswissenschaften |
| DDC class: | 600 Technik, Medizin, angewandte Wissenschaften / 610 Medizin und Gesundheit |